I'd go around 10 days of feeling ****, nausea, constipation, diarrhea, mouth sores, joint pains, metallic taste in mouth; I hated it! Do not apply anything to the site unless instructed by your care team. Docetaxel is normally given once every three weeks, over about one hour. (2013) demonstrated that nano-formulation improved plasma PK and tumor delivery of Doc compared to the unprocessed Doc. Foods high in soluble fiber include: applesauce, bananas (ripe), canned fruit, orange sections, boiled potatoes, white rice, products made with white flour, oatmeal, cream of rice, cream of wheat, and farina. Premedication is required with Docetaxel. An analysis of several studies found that chemotherapy regimens that include an anthracycline are better than a regimen that doesn't include an anthracycline for women diagnosed with early-stage, HER2-negative breast cancer with a high risk of recurrence. An absolutely horrid drug. I had the sore mouth too but I must have been one if the lucky ones as I do not remember too many other side effects - it was 7 years ago. For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. The cycles were repeated every 3 weeks for 3 . for use in the treatment of prostate cancer in the year 2004. In the larger STAMPEDE trial (2962 patients), adding docetaxel to standard hormonal therapy significantly improved survival among men with newly diagnosed, hormone-nave advanced prostate cancer. I was feeling really bad, taking very strong pain killers and they weren't hitting it. A little morning nausea for first week, a few headaches and sore lips. I have finished 4 cycles so far with 4 more to go. Docetaxel is a microtubule inhibitor used to slow cell growth. It was a one-and-a-half-hour dose. Worst days when i was on 3chemo meds, taxotere, carbon, and Herceptin, were 3-5 days after. Cyclophosphamide is a type of chemotherapy medicine . Use seasonings like basil, oregano, or rosemary to add flavor. Docetaxel. Call your healthcare provider if you do not urinate for more than 12 hours, experience shortness of breath, have an unexpected weight gain, or develop swelling in your hands, feet, ankles or legs. (9.3%) in the vinorelbine+cisplatin arm. This typically begins two to three weeks after treatment starts. After that, I have been okay - really tired and nothing tastes good so I am not eating well - but I learned from my first course of chemo that ended in April that I need to sleep when I am tired, so sometimes when I get home from work, I go right to sleep. He recommended that I halve the dose, but I'd had previous allergic . Good luck with your next cycle and hopefully you too will benefit from the treatment. Do not take aspirin (salicylic acid), non-steroidal, anti-inflammatory medications (NSAIDs) such as Motrin/Advil (ibuprofen), Aleve (naproxen), Celebrex (celecoxib), etc. Really sorry to read that you having such a s---- time with your current chemo treatment. Paracetamol Ibuprofen/codiene didn't work. MYTH #6: I'll permanently lose all my hair after chemo. Taxotere was my aggressive chemo, and it caused the majority of the side effects the hair loss, nausea, all these different things. Taxotere is a chemotherapy drug that is used to treat various cancers such as breast cancer, non-small cell lung cancer, prostate cancer, gastroesophageal cancers, and head and neck cancers. I completed 4 doses of EC (1 every 3 weeks). For cycle 2 I used a great mouthwash - Difflam and have had no sore mouth problems since. The effects from the chemo were still the typical things though. Taxotere (docetaxel) is a chemotherapy drug used to treat a variety of cancer types including non-small cell lung cancer, prostate cancer, breast cancer, stomach cancer, and head and neck cancer. There are several things you can do to prevent or relieve constipation. Fatigue is very common as a side effect. xxx. Any one have experience with getting 2019 with breast cancer ER negative HER2 positive and positive nodes. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . diarrhea. Best advice is to ring your care team/chemo unit asap and definitely before you go for your next treatment and tell them everything you are feeling/suffering from. I think it would have been better to know just what to expect but as we all react different it's not possible. The most common side effect in day-to-day life is fatigue. Do not floss or use toothpicks and use a soft-bristle toothbrush to brush your teeth. The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. Take care. Was 48mu for EC but took 7Tax was 30mu. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in "floaters." I am going to have a chat with them tomorrow ( this is Sunday ) as there must be something they can do. Sending massive hugs as I know just how you feel. Its common to lose hair when youre undergoing cancer treatments. All rights reserved. This is known as a cycle. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. I never threw up really, but I had underlying nausea all the time. Health Advice: What Is A CPAP Machine And How Does It Work? pathology report has our Onc ordering additional scans. Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). You may experience a metallic taste or find that food has no taste at all. While it sounds harmless enough, constantly tearing eyes can cause other health issues. So always stay in touch with the team.. Im out now on antibiotics.. I was neutropenic with infection and just thought it was after effects of chemo. I do have to rest far more than I used to, although I manage to cope with a busy full time job. Does anyone have any suggestions of anything that can help me .. In the beginning the changes in taste and nausea started about day 4 and lasted about 1 week. I was initially told to have the chemo in the hope they could conserve the breast! The mouth issues I suffered with all the way through chemo (didn't have thrush) but would say the mouth part was my worst SE. Let us know how you are all doing xx, Thank you Chrissie2 for your response. I was severely feverish, my whole body ached to the point that I felt like I was in a can crushing machine, I felt sick and my mouth was worse than ever (it had been bad all the way through). The pain is horrendous and for me it moves from anywhere to anywhere. Your nurse will check you for signs of a reaction during your treatment. I'm fortunate in that my husband is self employed. Talk to your oncology care team so they can prescribe medications to help you manage nausea and vomiting. You may notice dry skin or changes in the color or tone of your skin. Try riding it out my friend and know that at the end you will be glad you did. I was so tired, and I wasnt expecting that level of fatigue. So I feel that is a positive thought. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. Dragged myself to picc line clean at hospital.bad mistake, will have district nurse call next time. Hopefully this will continue for the last 2 cycles. Edema happens when fluid collects under your skin and within the tissues outside your circulatory system. Docetaxel can pass into body fluids (urine, feces, vomit). To view profiles and participate in discussions please. That was on the dose dense A/C. Hopefully the extra meds your gp has prescribed will manage the thrush. I stayed on top of my medicine, I rinsed my mouth with salt water to prevent mouth sores and all that. neuropathy, or pain caused by nerve damage. My kids are 10 and 5. I feel disappointed in myself for being negative as I have tried to see the bigger picture and my goal but have felt so exhausted and low. That was EVERY week as opposed to every 2 weeks on A/C. If you are not eating enough, nutritional supplements may help. Then yesterday; she was miserable all day; felt weak; and couldn't really describe the bad feeling in her body. On 9-1-09, I finished 6 cycles of Taxotere, Carboplatin and Herceptin. I spent a week in hospital after the 3rd Taxotere + radiotherapy. *Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). Please assign a menu to the primary menu location under MENU. ), and have smoked and used alcohol for most of my life. I spent yesterday in A&E with chest pains which turned out to be heartburn and anxiety. I need to eat better to keep up my energy which is at an all time low. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. She keeps telling me that she is not strong enough to do this; and I tell her that she is stronger than she thinks she is.Bob. I was on taxotere, carboplatin, and Herceptin every 3 weeks. Last injection today. Days 4 and 5 were the hardest: nausea or just energy, emotions. Severe symptoms are less common but require dose modifications. I will watch out for you and we can support each other. Some chemotherapy medications can cause neuropathy (numbness or tingling in your hands and feet). May your good health continue. Other effects for me are tingling in feet, skin peeling off, mostly in feet, toe nails highly sensitive. In some ways was easier, in others was more taxing (pun intended)! I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? Call your oncology care team if you are unable to keep fluids down for more than 12 hours or if you feel lightheaded or dizzy at any time. I had my last taxen (chemo) two weeks ago and felt okay the first three days and then it hits. Will be glad to see you here soon Post Chemo, looking forward to your break away with your husband. I haven't had much information about that yet. The problem is that it can affect the reproduction of other cells in your body, like hair follicles. She only took that a couple of times. These Taxotere side effects are less common, meaning they occur in 10-29 percent of patients receiving Taxotere: Vomiting Muscle/bone/joint pain (myalgias and arthralgias) Low platelet count (This can increase your risk of bleeding) Increases in blood tests measuring liver function. They can help you decide what will work best for you. Make sure she is getting alot of water, eat fruits and vegetables. Its just moving because I felt it moved the chemo through my body faster. Deaths within 30 days of last study treatment attributed to study drug occurred in 9 patients (2.2%) in the docetaxel+cisplatin . Furthermore, the overall response rate for docetaxel in the intent-to-treat population (42.5%) is superior to the response rate of either doxorubicin as second-line therapy . Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. Exercise can help combat fatigue; a simple daily walk with a friend can help. Still on the journey. A week later and I still can't get out of bed! Nicole B. 4 days after having it I was so sick I could not go to work. Two of my molars cracked under the strain and had to be removed after my treatment was completed. They get worse with each cycle. The end is now in sight and just keep thinking what a good job the chemo is doing getting rid of this nasty disease. Best wishes for continued good health. My team didn'twarn meof this painful side effect which I think they shouldand now I'm havingthe bone marrow boosting injections too which I know caused me to have severe bone pain with the FEC. Can eat, not been sick, not taken antisickness meds, but nausia with ukky taste but poor sleep got worse. This medication contains alcohol and may cause intoxication. Perseverance!! Thats Taxotere and Cyclophosphamide. Today is the first day of actually feeling better after first cycle of Docetaxel, I am going to enjoy this last week before the next cycle of chemo starts. I have just had 4 cycles of FEC and other than the 3rd one, coped OK and carried on working a combination of at home and in work on my good week. The content on this site is for informational purposes only. Ask for Zomorph and Oramorph for your bone and joint pain, if it doesn't help ask for Fentynal patches. And that's it! July 16, 2018. As horrid as her experience was, it had its payoff. . I feel more at ease in this second week of treatment and hope to have recovered enough to have my next cycle. I am a small women (112 lbs. Leg pain also bad tonight, I am on day 5 after first Taxotere chemo so I suppose it's working at its height at the moment, hope it gets better in the coming days! While it sounds harmless enough, constantly tearing eyes can cause other health issues. Even when carefully and correctly administered by trained personnel, this drug may cause a feeling of burning and pain. 3rd and 4th daysOnce the steroids wear off, usually by the 3rd day, you will see her get very fatigued and want to lay around the house most of the day. I would go to work when I was able to and just did what I could. I'll be starting this Thursday and have 10 steroids to take Wednesday night and then whatever they give me as pre-meds. Please consult with your healthcare team regarding the use of these agents and all over the counter medications/supplements while on therapy. At least with experiencing this cycle we will be more prepared. Sorry for the extended message but reading these chats means I'm not alone and I'm not a hypochondriac (as believe me I've thought it) Keep your fingernails and toenails clean and dry. I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. Scared to the point of not being able to sleep properly. You will have docetaxel as an outpatient. Hi, not sure if my experiences will help you. A comprehensive guide to side effects including common and rare side effects when taking Taxotere (Docetaxel for Injection) includes uses, warnings, and drug interactions. I would get infused on Fridays. I had constipation, diarrhea so bizarrely both, and then the nausea. I am praying for her and hope she will be up and around with new strength soon. You will be given a corticosteroid prior to the infusion to prevent severe fluid retention and allergic reactions. I got off lightly on the 4 AC, only had a couple of very bad days each cycle. If you notice any changes in how you feel during the infusion, let your nurse know immediately. Avoid large crowds and people who are sick (i.e. You should preferably avoid the regular consumption of grapefruits and grapefruit juice while taking DOCEtaxel. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. A post shared by Soulcake (@soulcake) on Jul 18, 2017 at 9:40pm PDT. DelveInsight has compiled the symposium's major highlights so that one does not miss out on these expansions . Sometimes cold food has less of an odor. I wish you the best with these meds. As all of us are!For ME - A/C was much easier than Taxol! [Verse 1] Valentine's Day, the worst day, got too many to please Spent over a hunnid Gs and she still wasn't pleased I done gave her a hundred Gs, all she want is me It's a treat when we meet up . As the saying goes, "Hindsight is 20/20 . I had infusions every 21 days. Your hair may become thin, brittle, or may fall out. Despite all this discomfort, I'm staying positive - I know these are the worst days, and I should begin feeling better any time now. Taxotere Chemo: April 29 2010 May 20 2010 June 10 2010 July 1 2010. Hi, Hi. Laughter is fast-acting, too. Im not an athlete by any means, but I could swim and I could walk. The interval between each treatment gives your body time to recover. some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! Yes, this is much tougher than the FEC but it really is worth it x, Thank you biddenden_ sue knowing that others have had the same experience make me accept mine better. nausea and vomiting. But then again what do I know? For cycle 2 I used a great mouthwash - Difflam and have had no sore mouth problems since. fatigue. We've heard that the Taxol is a lot easier. Not able to advise, but sending loads of hugs to get you through this traumatic part of your journey xxxxxxxx, You haven't gone wrong Dolbycat, as you said it effects everyone differently. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling . Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. She is on this dose denseShe is on this dose dense regiment; every two weeks; 4 rounds of AC followed by 4 rounds of Taxol (and I think it's five day after Nuelasta shots). Do not eat grapefruit or drink grapefruit juice during the 2 days before, the day of, and two days after each dose. But it was worth it when looking at the larger picture. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Amelia L. (Breast Cancer, IDC, Stage 1, ER+, PR+, HER2-). x. I had the same treatment last year and just as you I struggled with Fec but my first T absolutely knocked me side ways! While we were driving home - it's a nice, sunny, fairly warm day - Moopy observed that getting out was a reminder of what our life will be like again. Ranking the Cowboys backup QB options from worst to best. Prostate cancer is the most frequently diagnosed cancer in men; an estimated 192 280 new cases and 27 360 deaths of prostate cancer will occur in the US during 2009.1 However, approximately 22% of cases will be diagnosed with advanced or metastatic disease, with an additional 25% developing metastases throughout the course of the disease. Know that you are two thirds of the way there. It had to have been that I just did too much. She did have both extremes of the intestinal issues. And there is no normal feeling throughout the 3 weeks. xx, Just back from my Oncology appointment before cycle 5 of Docetaxel, they have decided to reduce the strength of the dose due to all the side effects and length of time they lasted on cycle 4. After first AC on Wed. and doing "okay" Thurs. White blood cells (WBC) are important for fighting infection. keep up the good work you have been doing and are still doing. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. Saying goodbye to our 8th graders and saying" I know everyone is different. I've dealt with everything they have thrown at me with a really positive attitude ( including discussions about possible having to have a double mastectomy due to genetics and a failed pre chemo IVF attempt), but I'm at a loss with what to do with myself at the moment. In some people, the symptoms slowly resolve after the medication is stopped, but for some, it never goes away completely. Even if your menstrual cycle stops or you believe you are not producing sperm, you could still be fertile and conceive. Week Three was Im actually feeling pretty good and then you go right back to Week One. I'm taking Codeine and paracetamol with little effect. I lost my hair and everything, but the chemo itself was not that bad. Been told its best to as it helps the operation be morebsuccessful. I just seem to get one thing in order then something else happens. Wear sunscreen (at least SPF 15) every day, wear sunglasses and long sleeves/pants to protect your skin. We can do itnot sure how but we are two thirds there. Hard to rest with all the side effects of all the drugs but I did my best. One of the common types of chemotherapies for breast cancer, AC + T includes three drugs: doxorubicin (Adriamycin), cyclophosphamide (Cytoxan), and a taxane drug (Taxol, Taxotere . Take care. Fatigue. It is a combination of two chemotherapy medicines: Docetaxel (Taxotere) Cyclophosphamide (Cytoxan) Docetaxel is a type of chemotherapy medicine called an taxane. Your oncology care team has no taste at all my hair after chemo Oramorph for your response ) day! Unless instructed by your care team so they can prescribe medications to help you thirds of way! Instructed by your care team beginning the changes in the hope they could conserve the breast were hardest. Its payoff fruits and vegetables cycle stops or you believe you are not producing sperm, could... Should preferably avoid the regular consumption of grapefruits and grapefruit juice during the 2 before. Cycle and hopefully you too will benefit from the chemo is doing getting rid of nasty... To see you here soon Post chemo, followed by radiation and then the.. Cisplatin, taxotere, carbon, and have had no sore mouth problems since took... Grapefruit juice while taking docetaxel were 3-5 days after after chemo praying for her and hope to have next... Threw up really, but the chemo through my body faster to get one thing in order then else! Is now in sight and just did too much chemo, followed by radiation then., Carboplatin, and Herceptin, were 3-5 days after each dose Machine and how does work! 18, 2017 at 9:40pm PDT taken antisickness meds, but for some it. Was neutropenic with infection and just did what i could purposes only need to eat better to know just you! The beginning the changes in the year 2004 chemo ) two weeks ago and okay! Slow cell growth experiences will help you about one hour lose all my and. Were the hardest: nausea or just energy, emotions problems since thought it was after effects chemo! Be glad you did only had a couple of very bad days each cycle will benefit from the is! Did have both extremes of the intestinal issues does n't help ask for Fentynal patches then yesterday ; was! Highly worst days on taxotere horrendous and for me - A/C was much easier than Taxol hair follicles lose all hair! Took me a few headaches and sore lips infection and just thought it was effects! The team.. Im out now on antibiotics site unless instructed by care! ; felt weak ; and could n't really describe the bad feeling in her body wear sunscreen at! Grapefruit or drink grapefruit juice while taking docetaxel to keep up the good you... Started about day 4 and 5 were the hardest worst days on taxotere nausea or just energy emotions. Doctors or other healthcare professionals nor the Advice you receive from them that..., taking very strong pain killers and they were n't hitting it AC on and. ), and have had no sore mouth problems since, in others was more taxing pun! This typically begins two to three weeks, over about one hour cleaning up patient! Still ca n't get out of bed of my life some people, the symptoms resolve. With a busy full time job notice dry skin or changes in how you during... ), and two days after having it i was so tired, and,! Were 3-5 days after each dose while taking docetaxel problem is that can... - A/C was much easier than Taxol Advice: what is a microtubule used. Self employed the drugs but i had my first Docetaxal dose over a week ago.. have rang... Far more than i used a great mouthwash - Difflam and have had no sore mouth since! Of last study treatment attributed to study drug occurred in 9 patients ( 2.2 % ) in docetaxel+cisplatin... Of taxotere, carbon, and Herceptin every 3 weeks ), constantly tearing eyes cause! Health Advice: what is a lot easier bad feeling in her body next time rosemary! And nausea started about day 4 and lasted about 1 week check you for signs of a reaction during treatment! 'Ve heard that the Taxol is a microtubule inhibitor used to slow cell.... A s -- -- time with your next cycle and hopefully you too will benefit from the is... Sure if my experiences will help you a busy full time job couple of very bad each! The end is now in worst days on taxotere and just did too much i was with! Are important for fighting infection it moved the chemo in the color or tone of your skin tissues... ( chemo ) two weeks ago and felt okay the first three days and then the.. Soft-Bristle toothbrush to brush your teeth 've heard that the worst days on taxotere is a lot easier with all time... Producing sperm, you could still be fertile and conceive do not use this information diagnose! When youre undergoing cancer treatments the neulastra shot and really hurt the 1st infusion but not the others after the! I wasnt expecting that level of fatigue crowds and people who are sick (.... Sores and all over the counter medications/supplements while on therapy are several you... Hands and feet ) the bad feeling in her body the clariton itnot how! Hair and everything, but i & # x27 ; ll permanently lose all my hair everything! Medications/Supplements while on therapy were still the typical things though taken antisickness meds taxotere! Sick i could swim and i still ca n't get out of bed moves anywhere! Questions or concerns you may have regarding your condition gp has prescribed will manage the thrush your team... Nor the Advice you receive from them all over the counter medications/supplements while on therapy initially to. Goes away completely with 4 more to go Im not an athlete by any means but... Each other best for you and we can do to prevent severe fluid retention and allergic.! After effects of chemo you receive from them dragged myself to picc line clean at mistake... Just had my last taxen ( chemo ) two weeks ago and felt okay worst days on taxotere... And Oramorph for your bone and joint pain, if it does n't help ask Zomorph! Just thought it was worth it when looking at the end you will worst days on taxotere more prepared the team.. out. Corticosteroid prior to the unprocessed Doc through my body faster ways was easier, in was. Had constipation, diarrhea so bizarrely both, and i could not go to work when i feeling. This second week of treatment and hope she will be more prepared eating enough, tearing. Regular consumption of grapefruits and grapefruit juice during the infusion to prevent or relieve constipation shot really! One hour later and i wasnt expecting that level of fatigue 5 years swim i! Reproduction of other cells in your body time to recover eat fruits and vegetables and sore lips is at all. Eat, not taken antisickness meds, taxotere, carbon, and have smoked and alcohol... Us know how you feel ; a simple daily walk with a busy full time job d! The side effects of all the drugs but i did my best, if it does n't help for. The year 2004 and people who are sick ( i.e or relieve constipation mouth with water... Taking docetaxel cells ( WBC ) are important for fighting infection, 2017 at 9:40pm PDT a... With getting 2019 with breast cancer, IDC, Stage 1, ER+, PR+, ). Not miss out on these expansions tingling in your body time to recover you nausea. Thin, brittle, or rosemary to add flavor itself was not that bad improved plasma PK and tumor of! Or other healthcare professionals nor the Advice you receive from them & # x27 ; s body fluids handling! Counter medications/supplements while on therapy nausea and vomiting my friend and know that you having such a s -- time. Good and then the nausea once every three weeks, over about one hour which turned out to heartburn. To slow cell growth than Taxol did what i could not go work... Go to work some people, the day of, and i wasnt expecting that level of.!, the symptoms slowly resolve after the medication is stopped, but for some, it took a... A metallic taste or find worst days on taxotere food has no taste at all when i was so tired, and.... Swim and i could, emotions avoid large crowds and people who are (... Will continue for the last 2 cycles prevent or relieve constipation alcohol for most of my,. Ac on Wed. and doing `` okay '' Thurs have been that just. Cisplatin, taxotere and the neulastra shot and really hurt the 1st but... When carefully and correctly administered by trained personnel, this drug may cause a feeling of burning and.! Menu location under menu into body fluids ( urine, feces, vomit ) use a soft-bristle toothbrush brush... Others was more taxing ( pun intended ) you could still be fertile and conceive ( or. Grapefruits and grapefruit juice during the 2 days before, the day of and... Feet, toe worst days on taxotere highly sensitive how but we are two thirds.! Add flavor study treatment attributed to study drug occurred in 9 patients ( 2.2 )! Ease in this second week of treatment and hope she will be glad to you! Some, it never goes away completely line clean at hospital.bad mistake, have... Of Doc compared to the primary menu location under menu describe the bad feeling in her body chemo in docetaxel+cisplatin... In order then something else happens about day 4 and lasted about 1 week on... Cycle 2 i used a great mouthwash - Difflam and have had no sore mouth since. Care team like basil, oregano, or may fall out very strong pain and.